Hello! I am very new to this site and DMT itself. I have successfully extracted DMT from M. Hostilis and got some nice very slightly yellow crystals (around 1g total). I don't have a pipe or vaporizer so I decided to try 2 methods: Sandwich and making my own vape cart. I tried the sandwich method numerous times and ended up wasting a lot as it would not work well no matter how hard I tried. So next I got some PE and CCell carts. At first I used 250 mg DMT and 250 µL of PE (Propylene glycol), this was said to give a breakthrough in around 3 hits. I tried and tried over several days but had no visuals when I closed my eyes, but I did have some visual enhancements and manipulation with my eyes opened.

I was pretty disappointed as I knew I haven't even come close to a breakthrough despite using the right ratio etc. However I did some paper maths and assumed a 500 µL cart has around 87 3 second pulls, which with my ratios of DMT / PE would yield around 3mg / pull, which to me this seemed extremely low... So I increased the ratio to around 500 mg / 250 µL PE. The effects were certainly more pronounced but again, almost no visuals in my head, no feeling of a roller coaster or blasting off, etc. I even tried going past 3 pulls and still nothing. Then I tried to meditate before hand, it helped put my mind at ease with the "pre-flight" anxiety, but again, nothing compared to what I have read and seen others experience.

Some background which may or may not help. I was on SSRIs (Lexapro 20mg) for a while until Feb 11 (day I got Covid-19, also the day I quit SSRIs due to the illness and did not take them again), I do have some mental traumas and issues that I am looking to solve, help, or at least understand more. Other than this I am not taking any other medications, I am fairly healthy physically, etc.

So I am just trying to understand what am I doing wrong? If anything? Why can I not see anything when I close my eyes, why does it seemingly take so much DMT for me to experience anything, and they are mostly visual, no gravity changes, or anything as discussed above?

Some help / guidance would be much appreciated! Thanks lads!

Do you have a natural resistance to other tryptamines?

You may need more while the rest of the SSRIs clear your system

Increase your dose by about 1/3 to 1/2 and see how that treats you.

You may also want to get acclimated with and build a relationship with harmalas. Their synergy with DMT may be your ticket to hyperspace admittance.

Don't give up. It's all part of the learning process

One love

Thank you very much! I honestly have no clue if I am naturally resistant to other tryptamines, I tried some psylocibin before, but I also did not have any effects at all even when I took 7g, however I had taken this closer to when I stopped the SSRIs. I have never taken anything prior to them so I have no frame of reference unfortunately. I will try adding an extra 250 mg (50% increase from 500 mg, 100% increase from the original 1:1 ratio recipe I followed) to the oil I have made already. I also have never tried with harmalas, nor have I done any research pertaining to its use. However, I will definitely look into it.

Some research I have done is relating to SSRIs and how they deregulate the 5-HT1,2 A receptors. Maybe this is the cause? Since I believe DMT is a 5-HT1,2 A agonist, and since I have less of them maybe this is the reason? I have also gotten St. John's Wort to see if I can up-regulate these receptors, but this takes a while but I am hopeful even though it has been several months since I quit SSRIs. I should also note I am NOT taking any MAOI's for obvious reasons.

Thank you very much for your response!!

The reason I asked is because there are some people that have naturally higher tolerance to drugs of all sorts. I've known people that needed a whole 10 strip of LSD to get any kind of effects, as well as people that don't respond at all to opiods.

I'd recommend doing some research on the half-life of the SSRI that you were on and the range of time it is expected to clear your system. My concern in relative to the contraindications between SSRI's and harmalas. IIRC, harmalas also don't mix well with ST John's Wort. Check the half-life on that one too. In these instances, the concern in around serotonin syndrome (as opposed to another concern with MAOIs, that is, hypertensive crisis from a build-up of tyramine, which MAO usually break-down).

Generally, also, people on SSRIs need bigger doses of tryptamines to get same effects as those not on SSRIs or if the person on SSRIs were not anymore.

Also, welcome to the Nexus

One love

Oh I do not plan on taking any psychoactive substances while on SJW, I am very aware of serotonin syndrome so I am currently trying to find ways to fix the issue if there is one while not taking anything that can harm me. Maybe I am just naturally tolerant I am not sure, that would require some testing of course, but it is also unfortunate because if true I would have to use even more of one substance for the same effect, essentially "wasting" material just because my body is different.

I also found the half life of my SSRIs to be about 30 hours, so in about 6-7 days it should have been completely eliminated. It has been about 85 days since my final dose.
Also thank you!

Hi Menthol.

Make enhanced leaf and smoke it in a pipe. That is all.