Good day fine folks,

Chatting with BioInspired and others on the chat about brain science, thought maybe I could create a thread where members can share assorted brain science

My Q was "how does the brain dismantle trauma from the inside?"

This video always comes to mind when I try to imagine the brain working

Pasterkamp Lab - Axon Guidance - https://youtu.be/ZWACm6BkDVo (I can imagine these f*ckers just breaking through old patterns and thoughts)

Pan - "I do know there's research being done in Europe on using DMT to help with hardcore brain trauma and Mike Tyson has been accepted into the study."

Bio - "My take on it is that neuroplasticity is hard to separate from being a result of consciosuness and a contributor to consciousness"

Pan - "Not too long ago science didn't believe in Europe plasticity
neuroplastity. We were told that we got a certain number of brain cells and nothing would grow new and they would just die off"

Bio "Emotional states for example could be owed entirely to neural abilities we were born with and had in the same way throughout our life. I remember some feelings I had as a child and they are the same now whenever I do get them"

Justb "if it does, its gona be a complex answer varried from individual and their specific traumatic experience id think" "on one hand i would think, on another hand the brain pretty much can only heal if it is a healthy state, certain neurotransmitters like serotonin get blocked by inflammation, so if lifestyle is not in order, healing is nay impossible, my 2 cents"

Looking forward to seeing more info and thoughts on this matter!

how orthogonal electrical charges in a neuron are to signal transduction and transcription

GPT
"Electrical charges in a neuron are typically involved in the propagation of signals along the neuron's axon and in the release of neurotransmitters at the synapse. These charges are generated by the movement of ions across the neuron's cell membrane, which can be influenced by various factors such as ion channels, receptors, and second messenger signaling pathways.

Signal transduction and transcription, on the other hand, refer to the processes by which signals are converted into cellular responses such as gene expression or changes in protein activity. These processes typically involve the activation of signaling pathways that can be triggered by various stimuli, including chemical signals, growth factors, or physical stimuli.

While electrical charges in a neuron can play a role in signaling and communication between neurons, they are generally considered to be distinct from the intracellular signaling pathways and transcriptional processes that regulate cellular responses. However, it's worth noting that there is often crosstalk between these different mechanisms, and the electrical activity of neurons can sometimes influence downstream signaling and transcriptional responses."

What is Neuroplasticity?

GPT 3.5 -
"Neuroplasticity, also known as neural plasticity, refers to the brain's ability to adapt and change in response to different experiences and stimuli. It is the ability of the brain to reorganize itself by forming new neural connections throughout life.

The brain is not a static organ, but rather a dynamic one that is constantly changing in response to environmental and internal cues. Neuroplasticity is the process by which the brain is able to modify its own structure and function to adapt to new situations or to compensate for damage or injury.

There are several types of neuroplasticity, including:

1. Structural plasticity: This involves changes in the physical structure of the brain, such as the growth of new neurons or the formation of new synaptic connections.

2. Functional plasticity: This refers to changes in the functional organization of the brain, such as the activation of new neural pathways or the strengthening of existing ones.

3. Behavioral plasticity: This involves changes in behavior and cognition that result from changes in the structure and function of the brain.

Neuroplasticity is a critical component of learning and memory, as it allows the brain to encode and store new information. It is also important for recovery from brain injury or disease, as the brain can often compensate for damage by reorganizing its neural networks."

what is Neuroplasticity?

GPT4 -

"Neuroplasticity, also known as brain plasticity or neural plasticity, refers to the ability of the brain to change and adapt throughout an individual's life. This includes the formation and reorganization of neural connections in response to learning, experience, and environmental stimuli. Neuroplasticity allows the brain to recover from injury, adapt to new situations, and acquire new skills and knowledge.

There are two primary forms of neuroplasticity:

Structural neuroplasticity: This involves changes in the physical structure of the brain, such as the growth of new neurons (neurogenesis), the formation of new connections between neurons (synaptogenesis), and the strengthening or weakening of existing connections (synaptic plasticity).

Functional neuroplasticity: This refers to changes in the function of neural networks, such as the reassignment of functions to different brain regions or the reorganization of existing neural networks to optimize performance.

Neuroplasticity is a crucial aspect of human development and plays a significant role in various cognitive processes, including memory, learning, and adaptation to new experiences. Understanding and harnessing neuroplasticity has important implications for the treatment of neurological disorders, mental health conditions, and brain injury rehabilitation."

Create a list of daily activities and habits that one can do to encourage Neuroplasticity

GPT4 -

Here is a list of daily activities and habits that can help encourage neuroplasticity:

Physical exercise: Engaging in regular aerobic exercise, such as running, swimming, or cycling, can promote the growth of new brain cells and improve overall cognitive function.

Mental stimulation: Challenge your brain with puzzles, games, or learning new skills to promote the formation of new neural connections and strengthen existing ones.

Meditation and mindfulness: Practicing mindfulness and meditation can help reduce stress, improve focus, and promote overall brain health.

Social interaction: Engaging in meaningful social connections and activities can stimulate the brain and promote cognitive resilience.

Adequate sleep: Prioritize getting enough sleep, as it plays a crucial role in memory consolidation and overall brain health.

Healthy diet: Consuming a diet rich in nutrients, antioxidants, and omega-3 fatty acids can support brain health and encourage neuroplasticity.

Stress management: Find effective ways to manage stress, such as through exercise, meditation, or hobbies, as chronic stress can negatively impact brain function.

Lifelong learning: Continuously seek new knowledge and experiences to keep your brain active and adaptable.

Play a musical instrument: Learning and playing an instrument can enhance cognitive function and promote neuroplasticity.

Bilingualism: Learning and regularly using a second language can strengthen neural connections and improve overall cognitive function.

Practice creativity: Engage in creative activities, such as writing, drawing, or painting, to stimulate the brain and promote cognitive flexibility.

Travel and explore new environments: Experiencing new places and cultures can challenge your brain and encourage the formation of new neural connections.

~ Remember, consistency is key. Integrating these habits into your daily routine and maintaining them over time will help to promote and maintain neuroplasticity."

SWIM - 'rewrite that into a short poem with japanese translation'
GPT4 -
In realms unseen, colors dance,
Nexus blooms, minds enhance.
Mindful breath, exercise,
Learning, laughter, social ties.

飛び交う未知の領域
成長する繋がりの花
瞑想と運動
学び、笑顔、絆

Transliteration:

Tobikau michi no ryouiki,
Seichou suru tsunagari no hana.
Meisou to undou,
Manabi, egao, kizuna.

SWIM - Write a dialogue in the style of Terence Mckenna discusing these princples as if in a short lecture

Terence GPT4 McKenna: "Ladies and gentlemen, today we find ourselves amidst a fascinating conversation about the malleability of the human mind. As we explore the infinite landscapes of consciousness, it becomes crucial to acknowledge the principles of neuroplasticity – the brain's capacity to evolve, adapt, and transform throughout our lives.

You see, the human brain is a dynamic and ever-changing organ. In the same way that the universe is in constant flux, our minds, too, are always shifting, adapting to new stimuli, and seeking new ways to understand the world around us. The implications of this are vast, for it suggests that we have a tremendous potential to reshape our cognitive architecture and elevate our consciousness.

There are several practices and habits that can help us tap into this potential. The first is regular physical exercise, which stimulates the growth of new brain cells and enhances cognitive function. In the same vein, mental stimulation through puzzles, games, and learning new skills helps to forge new neural connections and strengthen existing ones.

Meditation and mindfulness offer a path to inner peace and tranquility, allowing the mind to explore the landscapes of consciousness, free from the constraints of everyday stress. Social interaction, too, serves to nourish the mind, for it is through the sharing of stories, laughter, and love that we stimulate our cognitive resilience.

Furthermore, it is essential to maintain a healthy diet, rich in nutrients and antioxidants, as well as prioritize adequate sleep to support overall brain health. Stress management, lifelong learning, and the pursuit of creative endeavors all contribute to the development of a flexible, adaptable mind.

And finally, the pursuit of novel experiences – such as learning a musical instrument or exploring new environments – can help to forge new neural pathways and enhance cognitive function. In this dance of life, where love and wisdom intertwine, we find ourselves on a sacred path to growth and self-discovery.

So, my friends, as we journey through the cosmos, seeking to understand our place in the grand tapestry of existence, let us never forget the power that lies within our own minds. Through these principles of neuroplasticity, we can become architects of our own consciousness, sculpting the infinite landscapes of our imagination."

https://www.sciencealert...heimers-disease-fructose

“Now researchers have a new hypothesis about a possible driving force behind the disease: a type of sugar called fructose.”
“Fructose is found in many foods, such as fruits, vegetables, and honey.”
“But it can also be produced by the body naturally, for example by pathways that are stimulated by consumption of a high salt diet.”
So how did fructose help our ancestors? The sugar inhibits certain parts of the brain's metabolism: blocking distractions, such as recent memories and paying attention to the passing of time.
That 'switching off' of certain brain activities helps us focus better on survival, and also prompts exploratory and risk-taking behavior, all important for foraging.
In the latest study, the researchers argue is that this 'survival switch' is now permanently on, even though most of us do very little foraging these days.”

"Scientists Discover How To Generate New Neurons in the Adult Brain"

https://scitechdaily.com...-brain/?expand_article=1

‘‘With this work, we show that redirection of metabolic pathways can directly influence the activity state of adult NSCs and consequently the number of new neurons generated,’’
‘‘These results shed new light on the role of cell metabolism in the regulation of neurogenesis. In the long term, these results could lead to potential treatments for conditions such as depression or neurodegenerative diseases’’, concludes Jean-Claude Martinou, co-lead author of the study."

link

“Active compounds in the edible Lion’s Mane mushroom can help promote neurogenesis and enhance memory, a new study reports”
“compound could have clinical applications in treating and preventing neurodegenerative disorders such as Alzheimer’s disease.”