I now read many times that Mescalin purified is regarded by some people as somewhat more shallow and a reason is suspected to be the lack of some other alkaloids that get lost on the way. I wrote CIELO in the title, but that just goes to any mescalin TEK, simply CIELO is what I want to try and which seems to be the best TEK around this website.


But how would that be possible?

I now browsed Wikipedia and went through most of the compounds listed in Cacti. They all are just looking like Mescalin in a kind of way that they would not have any real different properties I guess?

I mean ...

switch position of 1x Me-O-group
or
add 1x OH-group
or
add 1x Me-O-group
or
add Me-group
or
remove Me-group
or
stick sidechain to ring with 2 bonds instead of 1

All kind of that stuff. But nothing that should really CHANGE the chemical behaviour of these compounds. And so I thought that when performing an extraction like CIELO you would also just carry over all of this.

I see no reason why 1x more methyl-group or 1x less Me-O-group or any other similar stuff would result in an active being not carried over into the final ethyl acetate and then being precipitated as an alkaloid salt.

So can we take it somewhat seriously that an extract will mostly just contain mescaline and lost some more actives on its way? Or might this be simply a common believe because *eating the whole product from nature* might always regarded as a more *full spectrum experience*

thanks for any insights

Adding an -OH group would make it insoluble in EA at high pH I think.

Stuff without -OH groups could make it through. However, endlessness has said that other alkaloids show up in trace amounts, so it may be hard to detect them in the poduct even if they make it through. Or maybe they stay behind. I don't know, but MS and NMR is not picking them up.

Thanks!

I'm really thinking about trying your CIELO method. It looks cool and I once grew mushrooms, but they are quite like LSD and therefore it lacks the joy of creating something unique with bare hands.

Now I will try to get such nice crystals and I guess will go for Bridgesii.

My question is:

"Which" Bridgesii should I get?

From what I read in the Phalaris Thread there are strains which are heavily active, others have nearly 0 Alkaloids. And this while even being from the same genus.

So I read something about also more potent cactus strains.

How do I know if I buy a strong strain or a weak one? How can I even know which strain I buy at all?

Now I browsed through the Internet and nobody ever stated that this type would be a certain strain ... always just *Trichocereus Bridgesii*.

So what do I do now? Just buy and hope for the best? Or always ask the person that offers? I guess they will not even know themselves

For me this is a lifetime quest without a simple answer.

Checkout endlessness' live database. Find and participate in the cactus growing communities. Get to know people who have been at it for years and absorb any wisdom they share. Grow as many different cacti as you can. Start a whole bunch form seed. When you learn about your favorite kinds, start a bunch more seeds with that in mind. Contribute.

You can focus on bridge, but I would also grow Pachanoi and Peruvians. At least some. You may be surprised by them. Sometimes the most neglected unassuming cacti surprise us with the most magic. Mysteriously, this has been a repeating theme.

Best of luck in your cacti growing adventures.

That sounds so amazingly written, I was not prepared for that answer

So I now bought some Panachoi + some Bridgesii. Let's say it as a simple question:

If a Cactus God would now start from stratch,

would he use some certain Keywords which contribute to very strong Cacti prior to his search?

Or would he just buy from various sources which label them as "T. bridgesii" / "T. panachoi" and see how far she gets?

Thanks for any clarification and yes, hoping to also get some insights. Also bought 1x BIG panachoi already cutted to directly try the CIELO, but I read that a cactus should first be placed in the dark for ~ 3 months?

Can't think of any keywords. If you are referring to clone names, I'm not gonna mention any. Not sure how reliable that really is.

Someone else can weigh in if they want.

Edit: Regarding the 3 month question:

I was just thinking about this once again. So you say -OH group stuff could be insoluble because they will be (-)O-R.

pKa of Phenol is ~ 10
Maybe for Mescalin analogues would be a little higher, because electron-pushing effects of MeO-R would reduce acidity probably (maybe little, but at least not increase).

pKa for Mescalin is ~ 9,56

So the standard base seems lime, ca(oh)2. What if you dont use ca(oh)2, but maybe na2co3?

It is weaker and should be strong enough for freebasing amines. But maybe will not deprotonate phenoles. So with na2co3 you might not loose the oh- alkaloids?

If that really would do this job chemically, it should make extraction of Anhalonidine, Lophophorine (if present also in non-Peyote) and Pellotine possible in 1 go.

Any reason why only ca(oh)2 is viable and that other method would not work?