Vinegar is not needed. Even in traditional yopo usage in south America it is custom to crush it up, base it and blow it up people's noses with a 'dart gun.
What you want to do is base it and extract it. It's more polar than DMT so it can be a bit trickier to extract pure if that is your aim.
BW's process is the most researched backed he has come up with the purest tek and he has backed it with analytical data,
https://wiki.dmt-nexus.m...W%27s_Bufotenine_Dry_Tek .
Feel free to check it out. There's a forum page too that may have additional data for you. I don't recommend heating xylene as he does in his tek.
As for 5-HO-DMT the body load is intense and not comfortable for majority of people, it's harsher to smoke too. Jonathan Ott recommended sublingal with harmala for memory, to reduce nausea and body load. It appears to be very vasoconstrictive.
Disclaimer: All my posts are of total fiction.