Synthesis wrote:The study quoted was new to me too:
https://pubmed.ncbi.nlm.nih.gov/33550376/I retired from the fitness industry a few years back already but used to be more up to date with the latest stuff, and would have probably done something very similar to what you'd likely recommend.
There so much I'd like to quote and go into more detail on but I don't have the time to re-read all the studies and brush up on the detailed pharmacology. (Which I know is lazy and makes me look like I'm talking shit). I will say I am by no means a endocrinologist.
Thanks for the link, I have a number of issues with this article. Proper PCT breakdown would have been good. 80% used PCT 20% didn't there's no breakdown of that data, just a summary. I mean at a blanket average there wouldn't be an overall difference to baseline because 80% of your data is from men who used PCT, in addition its not a good comparison size, such a big sample compared to a small sample. If they released the breakdown and data there may have been some statistical differences. I would have liked to have seen the exact data behind the 20% that didn't use PCT, what their protocol was and what compounds they used. They also only tested at the 3 month mark not 1 or 2 so there still is a strong possibility that PCT users bounced back quicker.
Again as I thought (and for clear ethical reasons) its not even close to a controlled study. There is no tests on how legit or potent their steroids were, if the PCT was pharmaceutical quality (steroids isn't easy to fake haha but PCT would be), there's no consistent cycle between the men in the study, they all had different stacks and esters, length, use etc.
I would also like to add none of those PCT regimes were consistent some started 1 week after last injection some 4 (its just guess work, would have been good if those men got bloods done to time it better with their PCT regime). It would obviously be down to what compounds are used and what esters to when the PCT should be started.
Some men used both tamoxifen and clomid which for memory they can interact (I need to re-read why I remember that being a thing). Not a major issue for memory.
And no HCG was used during cycle which is such a shame to not have that data. The point of it should be to be used on cycle to stop leydig cell damage (preventing testicular atrophy) and keep the natural test producing (trade off will depend on how one converts it). 1-3 weeks of HCG while your body's hormones are still stablising at a saturated dose I feel would be a waste. I've read doses 200-500ui a day causes too much aromatase activity which you obviously don't want especially just before or during PCT when your hormones are trying to bounce back.
You'll never get a perfect study unfortunately due to ethics but it still is an interesting study, there is just too many variables missing.
Synthesis wrote:
I also double-checked with one of the authorities on the subject, Peter Bond (author of Book on Steroids), and a good friend of the highly respected Lyle McDonald who runs the BodyRecomposition group and website and he seems to concur with the endocrinologist/professor's recommendation with regard to HCG usage likely not being effective.
Is their opinion on HCG use in regards to usage at the end, during a cycle or both?
Synthesis wrote:
As for test being overly subscribed, likely very very country-specific.
It definitely is. I would wager some of the low test cases are normal for that individual and many have other underlying issues that could be addressed.
I mean on paper who wouldn't want a testosterone boost, with all the benefits and this means many users will go from doctor to doctor until they find one that will.
Synthesis wrote:
But re the correct natural testosterone recovery, like you, I was/am still not 100% convinced that more traditional PCT's would not work - I was initially thinking tamoxifen, clomifene and HCG.
There's definitely a lot of data to suggest it wouldn't hurt. I don't know if there will ever be detailed data.
Synthesis wrote:
Did get 2 kids and the first was conceived towards the end of a tren/test cycle 6+ years ago if I remember correctly. Had continued administering 500-750iu of HCG every 3-4 days (something I'd be doing for the first 8 years of being permanently on). First try too - as in the first time I physically came inside her - I practiced ejaculation retention as I'd have something where the moment I'd cum one time (a few times if I was exceptionally crazy about her), I'd lose (sexual) interest. I loved this woman (she's my wife/mother of my kids now) so I did not allow myself to climax with her during sexual intercourse for the first part of our relationship.
8 years of continuous HCG, would have thought there would have been some down regulation there but it looked like it worked.
Synthesis wrote:
This whole issue of losing sexual interest and resorting to other types of sexual fantasies (nothing bizarre and interesting very test/AAS dependent too) is something I'll likely set as one of my intentions during some of the next Ayahuasca sessions.
Re a PCT I'm actually curious if you're PCT strategy would be the same (I have a feeling it might be). Background is 10 years on, with the first 5 years having 3-4 harder cycles (with tren), but mostly just being on test + mast, a bit of anavar and boldenone here and there. Last couple of years not done anything very crazy, though even if I go above 500mg a week (average), I'll still get some gyno stimulation, despite taking some AI's - mostly something that arose after gaining some sensitivity after an early very highly dosed (overdosed) AAS 'brand'.
But yea, like I said, the interest does not like in that anymore - even back then it wasn't really to gain massive size or anything like that, but mostly to maintain what I'd built and to lose fat more easily (the test etc helping with muscle retention, libido and energy during low-calorie sessions). At this point I'm not even too bothered with the current high amount of muscle loss (and libido loss - completely gone), I'm sure at some point I'll train to get some of it back. What's important is health, and energy - I have a strong belief that 'energy is everything' - and how physical energy is tied so closely to feeling good/happy/inspired, in a mode where one can create...but also emotion (energy in motion), and how the channeling of energies between different parts of our body can be so powerful - I'm not good with that yet (far from), but my wife upon take any psychedelic is immediately in that all-knowing/understanding Buddha like mode.
Look at the end of the day your literally fucking up your body and hormones. Its not evolutionaryily advantageous to be huge. It is a massive cardiovascular strain which at a evolutionary level we don't want due to how we use to hunt down food etc. In addition, at a evolutionary level our bodies don't want to and usually can't work that hard to maintain such size (genetically) it's literally why our bodies start pumping out myostatin to breakdown muscle growth so our bodies don't need to work so hard to maintain it. Also why body builders lose so much 'gains' when coming off the gear (as well as the drop in nitrogen retention/ water weight).
I've had a few friends naturally change their body compositions to the point you'd swear there on steroids but the amount of work, food, time and motivation is not attainable to the average man. Some of those guys were genetic freaks though. Did they look like Mr Olympia or were they as lean as some one on tren/ anavar stack? Fuck no! But they were genetically pushing their boundaries and put the average gym (steroid) user to shame. Yet, this brings us back to the temptation of steroid use its such a awesome shortcut, I mean you need to eat and train twice as hard when your on it but it allows you to do that due to faster recovery and increase energy/ appetite. It also helps get many over the "natural plateau".
Don't get me wrong I'm all about best quality of life at the best time but it's not maintainable. And there are drawbacks. Hence why there's so many trade offs. Tren is a classic example of something with so many draws back especially psychological. The increased libido is next level and i know a lot of men that wind up cheating on their partners while on it (when if they weren't on tren they never would have). I can't imagine doing a trip on tren, I rather do a trip post cycle when feeling flat than on a high dose tren cycle, way less of a psychological minefield.
I get why men stay on a constant cycle. Its so addictive, you feel good, lift more every week, get a confidence boost, libido boost etc so its hard to come off. The downside is the risks of long term damage increase. I mean there is some startling evidence coming out now for example even one time users developing glucose intolerance permanently. Is it enough to cause diabetes? Probably not but it puts you at a higher risk (this will be dependent on genetics too). And there will be more data eventually on other health issues I'm sure.
I do believe as a whole its safe but there are definitely compounds/ stacks safer than others and cycles easier on the body than others. Which is something I like discussing; there are definitely steroids one shouldn't touch. But I'll leave my opinion on all that for another day. Otherwise I'll be writing all day.
Ai use another point to talk about that men get wrong. Without bloodwork how do you know how much your converting? You do need a certain amount of estrogen on a cycle. You want to of-course avoid gyno but ya don't want to crash your sex drive or cause acne either. Hence why bloodwork is key. There's such a balancing act on auxiliary compounds and their usage depending on what anabolic compound you're using and how much, as well as your genetics.
By the sounds of it you have the right mindset now. Your issue will be breaking the addiction and dealing with less energy, losing the look, lower sex drive (temporarily), fluctuating moods, not being able to fuck like a pornstar (think tren) haha etc. Yet, I'm confident you'll bounce back, remember it'll be 18 months for all hormones levels to find that baseline again if that's the path you choose to take.
Synthesis wrote:P.S. I have a feeling we'd get along quite well in real. You seem to like the reasoning/science behind things too and seem to be quite strong in 'mind', yet also very interested in psychedelics. Happy to have virtually met you over here
Also quite a rarity to come across people who go deep in both these areas.
Yes likely we would. I'm surprised Ava69 hasn't weighed in.
Disclaimer: All my posts are of total fiction.