Sorry to hear about depression, I hope you or whoever is affected finds the chance to learn before approaching harmalas at least a few key things about this substance.
Some minimum requirements for this thread, and good starting points:
https://wiki.dmt-nexus.m...d_constructive_drug_talk (be careful when asking for medical advice! a doctor's opinion cannot compare to forum advice)
It could be perceived by you as a treatment for depression or a symptom management aid, effective or ineffective, what is important is reducing harm or making things worse.
For this, look at the interactions table
https://wiki.dmt-nexus.m...ctions_and_their_effects and
AVOID interfering with prescribed medications or doctor's advice.
The ROI depends on the form the extract is in: freebase or salt (the type of salt I know is HCl covalently bound to a harmine or harmaline molecule, as seen in the harmala purification guides on the
Nexus Wiki). I can only vouch for the HCl extract (salt), ingested orally, because it's the only one I tried, but I have read reports of smoking freebase.
Beware of excess dosage because side effects as extrme ataxia, vomiting, nausea can appear.
Try learning more about what "30x" means in your particular case, how accurate this rating is, apply the mathematical conversions knowing that harmala seeds can contain up to 6.5% harmala content by weight. I'd be at least somewhat skeptical of the 30x rating, but it sounds very potent.
The links and the wiki are good starting points, and try searching for threads or asking for threads in chat or filtering by experienced users or moderators.
Good luck and happy learning