Yes, that is absolutely possible. Mandrake grows in the wild here, so I can try that when the winter is over. Do you know anything about the usual alkaloid profile for mandrake?

Mandrake root is about as potent as Datura stramonium seeds. It's from 0.2-0.6% alkaloids. I've seen conflicting data on it. Some say it's nearly pure hyoscyamine. Others say it's a mix of hyoscyamine and scopolamine with hyoscyamine being the main alkaloid, much like Datura stramonium. But I’ve seen other reports saying the opposite.

There are surprisingly little studies done on mandrake. You would think that because of its huge popularity in books that more studies would exist on it.

Be careful using it. You only need a tiny bit of dried root. About 50 mg of dried root is equal to about 5 Datura stramonium seeds.

Another good option is henbane which is also said to be primarily hyoscyamine.

Hyoscyamine is the best of the tropane alkaloids when it comes to potentiating psychedelics. Scopolamine is much less desirable because of its pronounced sedative effects and stupefying effects. Scopolamine is far more likely to cause delirium.

It would be nice to find a plant that contains only hyoscyamine.

holy shit thats something im definately going to try

SWIM really didnt like lsd and spice, lsd prevented spice effects to be deep, it was some visual alterations that people might find nice but for SWIM it felt very 'incomplete' somehow

Evening Glory, just keep in mind that there are two kinds of plants called Mandrake. The American Mandrake is not true Mandrake, it is toxic and doesn't contain tropane alkaloids.

Oh yeah, of course! Mandragora officinarum is the one I am looking for. I have found it in the wild here before, so I should be able to find it again. Too bad I didn't take it with me the last time... Thank you for all the great info, ron!

Take a look at parts 1.7(medicinal uses), 1.8(chemistry) & 1.9(medicinal properties) in this dissertation on bacopa micropropagation.

Micropropagation of Bacopa monneiri L. Penn.
- an important medicinal plant


Ayurvedic info sheet on bacopa, detailing the effects as seen through the perspective of Ayurveda:

http://www.herbalayurveda.com/downloads/brahmi.pdf


Past this, you can google 'bacopa research studies' to find more information.

SWIM usually smokes cannabis when on a acid-trip. It can boost the trip in a good or bad way. In bad I mean as already mentioned, you become stupid. But then again that can be fun

LSD and Cannabis interact badly for this SWIM when he is tired because of Getting up early and staying up all night.
It really caused him severe "Stupidity" like that .

I rarely try a new LSD source without cannabis handy. If it turns out to be too weak, just smoke up to get the visuals and euphoria going. A bit foggy mentally, but you can retain some of the entheogenic aspects if you remember to write down your epiphanies.

The best two acid combo's i know of are LSD with oral cannabis and LSD with passionflower.

Oral cannabis is absolutely fantastic with acid. Much better then smoked cannabis. You'l have very spectacular visual effects, an immense sense of euphoria and a strong enhancement of the psychedelic effects of it.

Passionflower is even better. The LSD becomes a psychedelic that's fully equal to DMT, this way. But it still remains it's own unique character. The effects of this combo are very hard to describe because they totally surpass those of plain LSD, but are different from the effects of any other psychedelic this powerfull.

Datura is very synergistic as well and indeed also nux vomica.
I don't like alcohol with it that much, although the effects are funny. It makes you feel incredibly strong.

Fly-agaric has a good synergistic effect as well in moderate doses.

Another thing that's very nice: a large dose of LSD first, and on the come-down a very small dose of it again. It's the best cure against the fatigue at the end.

LSD and MJ - very nice. Quells the nausea a bit, boosts the visuals, and gives you a high mindset. I like a trip with or without however.

LSD and mushrooms - eh. Like a cloudy acid trip or a mushroom trip with too many visuals. Makes the body high uncomfortable. Very dehydrating.

LSD and MDMA - wow. Definately not an acid trip. So bright, so euphoric. Changes the attitude and the visuals. Definately one to try.

LSD and 2ci - now that's an experience. Dance. Laugh. Have a solid 24 hours AT LEAST at your disposal. Very bright and colourful journey.

LSD and alcohol. - depends. Drink on acid: not too much. Slows you down a bit and lets you sleep. Eat acid drunk: May turn you into a retard trippin balls if both doses are high. SWIM does not recommend.

LSD and NO2 - comic book land. Totally sweet and worth trying.

LSD and DXM - weird... only only only way to describe it. Keep both doses low and with a close friend. Prepare to embark on a journey.

I concur!

also LSD and N02 definitely has to be experienced

Has anyone here tried calamus with LSD?

SWIM has been recently playing around with calamus and finds it to be a very good booster of other psychoactives. A weak brew of calamus and coffee is very nice. It’s got sort of a mescaline-like feel to it. It’s not psychedelic, but has a “feeling” that’s similar to a low dose of mescaline. I’m wondering if a small amount of calamus, say 4 grams extracted with cold water overnight, would make LSD more like mescaline?

NOTE: SWIM recently had an overdose of a calamus extract (10 grams extracted with acetone) which was very unpleasant (he vomited over and over for many hours). So be careful with this herb. It’s nice in small doses only. Water extraction seems best. Acetone extracts too many emetic toxins from the root.

Did calamus with LSH. Didn't make it mescaline like, but did potentiate it quite a bit. It became more LSD-like, visually.

How much calamus was used, and how was it taken (chewing it, taken as tea, etc.)?

It was a standardized extract that was sold in dutch smartshops. They don't sell it anymore, unfortunately. It was very concentrated, so half a teaspoon was enough to definately notice effective potentiation.

i will likely be trying out this combo next week. when do you think i should dose on the spice? i was thinking maybe just before the peak, so that as i came down from the spice it would kinda ease back into the 'cid. any suggestions?

I concur that LSD + DMT is absolutely sublime, (was for myself and 2 friends anyway). I'll go you one better though...LSD and caapi leaf changa. Absolute, multisensory nirvana...

One time, quite a few years ago now during my MDMA/LSD/mushroom/marijuana honeymoon period, I has an incredible MDMA + LSD experience. 2 strong, clean pills, and 2 drops of fiendishly powerful LSD. Incredible synergy...had an absolute blast AND did a lot of therapy that eve...had been in a weird place before that night, blow torched the negativite thoughts right out of me. Never got anywhere near this place again though on future attempts, so long ago I ceased trying. Like Alan Watts said, "When you get the message, hang up the phone."

And marijuana, on the gradual come down..especially out in the sunshine, with some nice dubby tunes playing...tops.

And yeah, cost of a few hits of LSD each...£20...dropping it with close friends...priceless

this is something i have alot of experience with...here are my favorite combos;
7lsd, 2mdma, 1 fat joint laced with a shit ton of dmt on the peak
7lsd plus 20mgs of 5meo(lsd cut the nausia...like easing into a hot bath instad of jumping in and burning your balls)
one that probally wont be done any more but is/was my favorite dubbed the pupple swirple 80mgs amt plus 7lsd plus a fay joint with n,n or a big blast of 5meo
i used to be crazy in my days

one thing i have noticed about the use of dmt on other psychedelics is that it shortens their duration...where as amt would last for a solid 24 or more...i could smoke dmt several times and be able to sleep in 12
kind of like batteries...in a remote the last forever but in a camera with FLASH less than a day