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Enteric delayed release capsules for pharma Options
 
fog
#1 Posted : 4/23/2020 11:50:07 AM
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Posts: 25
Joined: 20-Apr-2019
Last visit: 17-Dec-2022
Hi folks!

So I was researching capsule dissolve times and discovered a thing called enteric capsules. Here's a description from one company:

"Enteric capsules work by utilizing the different acidic and alkaline pH characteristics of the different parts of the human digestive tract. The human bodyโ€™s overall pH hovers around the neutral range of 7, but different parts of the body have varying internal pH levels.

The human stomach is acidic, with a pH of 1.5-3.5. This high level of acidity is what enables your stomach to breakdown the foods you eat for proper digestion.

After the stomach, the acidity decreases to an almost neutral level in the duodenum, before the pH increases in the small intestine to the slightly alkaline pH 7.4. Capsuline Enteric capsules are made with plant-derived HPMC and HPMCP, the latter is the enteric ingredient that only breaks down in environments with a pH of 5.5 or higher, allowing the capsule to pass through the acidic environment of the stomach (pH of 1.5-3.5) without dissolving.

In other words, this means that they pass through the stomach intact, and then dissolve approximately one to two hours after ingestion when they reach the alkaline environment of the small intestine."

This looks perfect for avoiding pharma nausea! Send in the harmarlas in regular capsules and the dmt in these. Onset will be delayed but well worth it for people struggling with nausea and premature purging. Kind of like plugging but without the butt stuff lol.

What do you think?
 

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EphemeralTruth
#2 Posted : 4/23/2020 5:19:22 PM

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Posts: 111
Joined: 10-Nov-2019
Last visit: 24-Jan-2021
Try it and let us know Smile

I'd say my concerns would be:

1. Is DMT absorbed as well in the small intestine vs stomach?
2. Is an MAOI effective and/or necessary in the small intestine?
3. The MAOI might run out too soon unless you take it significantly after the DMT
 
 
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