Sit down, close your eyes, take some deep breaths, and go for it. It will be scary at first, but you'll very quickly realize everything is ok and then "hey, this actually feels pretty good!".
You can always do a small dose to get familiar with the body high before you go fully kaleidoscopic.
I don't want comfort. I want God, I want poetry, I want real danger, I want freedom, I want goodness. I want a clever signature.