DISCLAIMER: As I mention a lot of times in the write ups this is not supposed to be a bulk TEK, however, it can work in large amounts. Obiously, not in an amount of say 5 pounds of material to procces. If this same TEK was to be use in a large scale(100 pounds) it would to be adjusted. This is not a good write up, I plan on wirting a better one

Hi, I want to make a write up of this incredible TEK that is rarely mention and find incredibly usefull. This TEK is extensivly used by LSD alchemist to extract their amine(LSA or Ergotamine) in large amounts, of course it can be aplied to small amounts. I don't intend to tell people this is a bulk extraction, it can be used to extract any quantity. LSD chemist also like this extraction since it gives a reasonable yield with high purity, aldo SWIM is planning on recristalizing on ethanol. There is another way SWIM knows to extract purer product that is mainly used in Europe, this one uses magnesia as freebasing agent in a solvent of ethyl ether or benzene, this one is not pretty easy since magnesia has to be growned up and for large amounts it is unpractical and with the other method for SWIM is better. So the method I am going to teach you we are going to use amonium hidroxide as freebasing agent in a solvent of cloroform, I SWIM calls it the USP method. However, we have to talk about somethings before continuing before jumping into the TEK.

Basic precautions

Let's not forgot we are working in LSD chemistry now and aldo this is a pretty easy procedure for an amateur chemist it should be still noted that some precautions must be taken in order to make sure we are succesfull. Our final product is very estable inside the plant material. But once we pulverize it, it is very vulnerable to light and heat, there is also the risk of the product degrading in a short period of time. To protect against light we should work under a red or yellow photographic light and away from an UV exposure. To protect from heat it is important to not heat anything above 40C. How to prevent the degradation of the product will be covered in the section of the TEK "Conservation" however it is not recomended to store it for a long time. It must also be noted that being quick in extracting the goods is important to avoid spoiling the product.

After covering how to make sure the product is safe during the extraction, it is important to keep the alchemist safe. The LD50 of ergot is around 100mg/kg in a rabbit and for LSA 16mg/kg on a Guinea Pig. There is no data on human animals, but one can conclude something, if working with large amounts of seeds or ergot one could be risking his life if care is not taken. If you plan on extracting LSA from mlre than 64 HWBR seeds(1mg per 4) he is alredy asuming a big risk of LSA poisoning. That is why LSD chemistry is only practiced by the experienced, a drop of concentrated LSA down your throat is really dangerous. However, that won't ruin our fun, we just need to be carefull. Protecting ourselfs with thick gloves, lab suit, goggles and respirator protection is essential. For more details on the protection used I recomend you read the MSDS of LSA, the protective measurements part especially, every care taken there applais to ergotamine.

Solvent care

Dealing with excesives amounts of solvent is quite difficult, from obtaining to siposing it. But there is one key, reuse recycle. After the defatting step you can distill the solvent from the fat and have new fresh solvent, it is very easy. I am not going to go in depth on how to obtain solvent, it is against the rules :o , but in order to dispose it is to call a waste company instead of stick it underground. On a small base it is not much of a problem, but when working with big quantities of solvent this tips gain importance. Something that is crucial too succed is to make sure the solvent is pure, for checking it we simply make an evaporation test. For that we simply heat(on the microwave for example) a piece of glass(microscope slide) and drop some solvent in it. If it is pure it will leave no resediue. If it leaves re-distill the solvent or buy a new one.

Materials And Ingredients

Solvent(nafta, hexane, petroleum ether or ligroine) It would be needed around 5 times more solvent compared to the weight of the plant material(Ex:28g of seeds would need roughly 140g of solvent) Aldo have more on hand just in case.

Amonium Hydroxide 100ml usually. More detail later

Cloroform 900ml usually. More details later. Aldo we will need some more.

3% Tartaric acid. Not very much around 10mg per 100mg of product to disolve in

Saturated sodium bicarbonate solution, not much to be said.

Vacuum Desecator. This is used to evaporate liquids dry without heating anything over 40C. There might be other options, but I think a small vacum desicator using some jars and syringes is something cheap and easy to build. Good enough for small scale experiments.

1500ml-2000ml Separatory funnel. To create the extraction solvent. A smaller one might come on handy when extracting the tartaric acid solution, aldo a syringe might work.

A small sep funnel 100ml will work

Cromatography colum. To defat the seeds or ergot

Basic glassware(Beakers or similar and mesuaring cilinders. Also a scale)

Eye droper. To disolve the product in the tartaric acis

A flat glass piece. Like a microscope slide for example.

Let's beguin!

First step: Powdering

We start by powdering the seeds/ergot. A blender should do it. I found that powdering seeds is very difficult do to dampness. The way too go is to grind a bit the seeds and air dry them, then powder them completly. Once the plant material is powdered our product will degrade quickly,so we have to move quickly. Now we will cover the powder with the deffating solvent to form a slurry, like a soup. There are a variety of solvents to choose, nafta, hexane, petroleum ether or ligroine. They all work equally well.

Second step: Deffating

Now we are going to prepare ourselfs to defat. We will prepare the cromatography colum and pack our slurry in it. We will atach a separatory funnel(Or similar) on top, and we start dropping the solvent in which the seeds are covered in through the chromatography colum for some hours. The idea is for the solvent to carry away any oils or fats remaining in the plant material. We should check periodically for this by doing an evaporating test(See solvent care)

Third Step: Extracting

The third step is the most controversial but the most fun. We pack in our big sep. funnel we pack 100ml of amonium hydroxide and 900ml of cloroform. Then we shake vigorously and collect the botom cloroform layer, this will be our extraction mixture. We could do more or less extraction mixture we just have to keep the ratio of cloroform to amonium hydroxide 9:1
Then we pack the mixture like before in a separatory funel(Or similar) above the cromatography colum and start dripping extraction mixture through the column. This will get all the goods out. We will do this until what comes through the colum does not glow under black light, that will indicate that there are no remaining alkaloids in the plant material. Now we have a mixture of lysergic kind alkaloids in our extraction mixture and for so we will change our pure alkaloids to the tartare salt and further purify.

Fourth Step: Change To Tartare

We will first evaporate our extracts, and we will do this under vacuum in order to avoid heating over 40C(and burning our product) or exposing it to light. We are evaporating to drynes to have all the impurities mixed with LSA or Ergotamine. Once we have a solid extract we will re-disolve it in the least quantity of tartaric acid(3%) This will change the freebase alkaloids to the tartare salt. Now, after disolving in tartaric acid we can actually know how much product we will obtain. We can aproximately know the amount of moles present by coloring the solution with an acid-base indicator and titrating with this acid. However, if you don't want to know you can just proceed directly to the next step. We will transfer our tartaric acid solution to our small sep. funnel(In small quantities a syringe might be better option) rinsing the flask were we had our solution with some tartaric acid(3%) Now we will make the solution basic with saturated sodium bicarbonate solution. Then we will simply extract with two equal volumes of cloroform. We combine the two cloroform extracts, we evaporate to dryness using a vacum. Yielding nice LSA or Ergotamine in a reasonable purity.

Storage of LSA

We can simply store the LSA in ethanol with anti-oxidants(Fumaric acid, for example) when we want to use it we just evaporate it and use it. However, it is essential to store it in cool temperatures. This will provide a long self-life. However, it is recommended to use it as quickly as possible. To store ergotamine we will simply store it in the freezer, Ergotamine won't last for too long in this conditions, but I can't think of other way.

Dosage and Usage

First of all I don't encourage anybody too use it. And the dosages are based on the theory, and not have been tested. Anyway I can't think of any reason to selfmedicate with this substance. I see more future on using it as a precursor for LSD, but I will make this section anyway.

The dosage I think is right is of 1mg. This is supported because, 4 seeds of Hawaian Baby Wood Rose makes an ideal dosage for a trip. Each of this seeds contain 250aug of LSA. So 1mg would be enough for the trip, using the same rule we can figure out the dosage of pure LSA based on how the trip with seeds went.

The dosage for ergotamine, should be thesm same. Based on Ergotamine content in Cafergot.

Notes:
1) English is not my first language, and it is bad. This write up is not defenite and has a lot of mistakes, furthermore it was done in one sitting. Support from the alchemists of the forum would be greatly thanked
2) I found another paper that made the same extraction solvent but changing the recepie a little. In the paper 10ml of strong ammonia solution (28% NH3OH; 56% NHtOH), 90ml of methanol and 900ml of chloroform were mixed. This won’t give a two layer separation, but an omogenus mixture. I think this option is worth trying since the use of ammonia is less than the recepie I give here
3) I have seen people air dry solvents in this kind of cases and giving good yields, I might be a bit paranoic
4) I will try and run theTEK and give pics, but I don' own a chomatography column and most solvents listed in the deffating are incredibly rare to find OTC in my country(but not in USA, don't worry
5) A longuer write up has been made