admittedly, copied from wiki, with some additions from bluelight.

Opioids
α-methylfentanyl, became well known as "China White" on the heroin market
parafluorofentanyl
3-methylfentanyl, extremely potent opioid, allegedly used as a chemical weapon by the Russian military in the Moscow theater hostage crisis
MPPP, especially infamous due to an impurity in some batches called MPTP which caused permanent Parkinsonism with a single use[26][27]
O-Desmethyltramadol
7-Acetoxymitragynine
4'-Nitromethopholine

Hallucinogens
Lysergamide-based
ALD-52, N-acetyllysergic acid diethylamide, famously believed have been the active ingredient in the "Orange Sunshine" acid of the 1960s [nick sand states that all of the orange sunshine was just straight LSD.]
ETH-LAD, 6-ethyl-6-nor-lysergic acid diethylamide ETH-LAD is a hallucinogenic drug an analogue of LSD.slightly more potent and with subtly different effects, described as less demanding.
N-Morpholinyllysergamide (LSM-775) is a derivative of ergine. It is reported to have some LSD-like effects at doses ranging from 75 to 700 micrograms.
D-Lysergic Acid Ethylamide, (LAE-32) is a derivative of ergine. It is reported to have some LSD-like effects but is weaker and shorter lasting
N-Pyrrolidyllysergamide (LPD-824) is a derivative of ergine. It is reported to have some mild, short lasting LSD-like effects at a dose of 800 micrograms.
N1-Methyl-Lysergic Acid Diethylamide (MLD-41) is a derivative of LSD

Tryptamine-based
4-Acetoxy-DiPT, N,N-diisopropyl-4-acetoxytryptamine
5-MeO-AMT, 5-methoxy-alpha-methyltryptamine
5-MeO-DiPT, 5-methoxy-di-isopropyltryptamine (also known as "Foxy" or "Foxy Methoxy" )
5-MeO-DMT, 5-methoxy-dimethyltryptamine
5-MeO-MiPT, 5-methoxy-methylisopropyltryptamine
AMT, α-methyltryptamine
DiPT, N,N-diisopropyl-tryptamine
DPT, N,N-dipropyltryptamine

Phenethylamine-based
2C-B, 4-bromo-2,5-dimethoxyphenethylamine
2C-C, 2,5-dimethoxy-4-chlorophenethylamine
2C-D, 2,5-dimethoxy-4-methyl-phenethylamine
2C-E, 2,5-dimethoxy-4-ethyl-phenethylamine
2C-I, 2,5-dimethoxy-4-iodophenethylamine
2C-T-2, 2,5-dimethoxy-4-ethylthiophenethylamine
2C-T-4, 2,5-dimethyoxy-4-(i)-propylthiophenethylamine
2C-T-7, 2,5-dimethoxy-4-(n)-propylthiophenethylamine
2C-T-21, 2,5-dimethoxy-4-(2-fluoroethylthio)phenethylamine
DOB, 2,5-dimethoxy-4-bromoamphetamine
DOC, 2,5-dimethoxy-4-chloroamphetamine
DOM, 2,5-dimethoxy-4-methylamphetamine
TMA-2, 2,4,5-Trimethoxyamphetamine

Dissociatives
3-MeO-PCP
4-MeO-PCP [28]
Dizocilpine (MK-801; (+)-5-methyl-10,11- dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine)
Eticyclidine (PCE; CI-400; N-ethyl-1-phenylcyclohexylamine)
Rolicyclidine (PCPy; 1-(1-phenylcyclohexyl)pyrrolidine)
Tenocyclidine (TCP; 1-(1-(2-Thienyl)cyclohexyl)piperidine)
[edit]Piperazine-based
BZP, 1-benzylpiperazine
mCPP, 1-(3-chlorophenyl)piperazine
MeOPP, 1-(4-methoxyphenyl)piperazine
pFPP, 1-(4-fluorophenyl)piperazine
TFMPP, 3-trifluoromethylphenylpiperazine, has the unique distinction of being the only drug to be emergency scheduled into Schedule I and then allowed to become legal because the DEA was unable to justify permanent scheduling

Entactogens
4-MTA
5-Me-MDA
AET, α-ethyltryptamine
Butylone
Ethylone
IAP
MBDB
MDAI
MDMA, 3,4-methylenedioxymethamphetamine
MDEA, 3,4-methylenedioxy-N-ethylamphetamine
Methylone
MMA
PMA, a highly dangerous amphetamine derivative responsible for many accidental deaths
PMMA, similar to PMA
PMEA, also similar to PMA

Stimulants
α-Pyrrolidinopropiophenone (α-PPP)
2-Fluoroamphetamine
4-Fluoroamphetamine
4-Methylaminorex (4-MAR)
Buphedrone
Desoxypipradrol
Dimethocaine
Diphenylprolinol
Ethcathinone
Flephedrone (4-FMC), and its 3-fluoro isomer 3-FMC
Geranamine
MDPV
Mephedrone
Methedrone
Naphyrone

Sedatives
GBL, gamma-butyrolactone, both a precursor to and substitute for GHB
1,4-Butanediol, another GHB analogue
GHV, gamma-hydroxyvaleric acid (4-methyl-GHB)
GVL, gamma-valerolactone
Methylmethaqualone, an analogue of the sedative methaqualone
Mebroqualone
Phenazepam
Premazepam

Cannabinoids
THC-O-acetate
JWH-018
JWH-073
JWH-200
JWH-250
CP 47,497 and ( C8 ) homologue
CP 55,940
HU-210


shoes notes:

This is by no means a 'list of all drugs ever'. You should have a look here for that, although that is not a definitive list by any means either.

Some of the artificial cannibinoids listed there show great medical promise for the future, with effects including appetite stimulation, appetite suppression, reduction of stress and anxiety, etc.

.
.
Thanks, I grabbed my grocery list by mistake...




4 aco dmt is one I've been interested in given its friendlier than psilo****** effects but can't shell out money for maybe's. Perhaps a TEK will arrive that can modify our beloved spice...<wishful>



Namaste,

J
.
.

4acodmt >>> 4hodmt

I have a list like this for entheogens too.

Im telling you guys, modification of alkaloids via immobilized enzymes is the future of clandestine drug synthesis.

its just getting a hold of the specific enzyme.. although, as I write this I realise that it is *very* possible.
just obtain plant species, and if one knows the molecular mass of the enzyme, lyse the cells and
we could centrifuge and purify to obtain the enzyme. then immobilize.
but ... this is just theory.

Just??

I presume your knowledge in molecular biology is not that great Getting a hold of a specific enzyme is a pain in the ass. For once, you'd have hard time finding enzymes that do what you want. Go find me an enzyme that acetylates psilocin.

For another, using centrifugation to purify a certain enzyme is the most wrong way to go. You actually want to overexpress the enzyme in question in some bacteria or yeasts and purify it from there using some chromatography.

I love this place, I learn so much here. I hear the words peptide coupling thrown around when talking about the future of synths.

infundibulum:
I see your point, in order for this to work, there must be an enzyme which does
what you want to your precursor. So, I retract my statement "the future" of
clandestine drug synthesis. But, perhaps something which has been greatly overlooked. But
I know for sure no one has gene splicing enzymes or the microscopy to do it at home,
so that option is out.

I'd sure love to see a bunch of imobilized tryptophan decarboxylase going to town
on a solution of tryptophan. Does it need NADPH? NAD+? That'd be such a rush

Psilocin acetylation:
while I can't find that specific enzyme, here is something you may be interested in..
http://www.shroomery.org...of-Psilocybin-Production

as a side note; tryptophan enhanced substrates have been shown to significantly
increase the production of psilocybin.

visualdistortion: I think what you mean is there was an article released a couple of years ago pertaining to the synthesis of LSD from LSA, using expensive peptide coupler reagents; PyBOP (or the more carcinogenic BOP) http://en.wikipedia.org/wiki/PyBOP. The guy is now in prison, but the jist of the article and the reason it caused so much excitement is because it completely avoids the use of nasty, unobtainable hazardous chems like Hydrazine, SO3, SOCl2 or the like.