When I fell very depressed, overwhelmed, dull and gray, a low-medium dose of DMT always brings me right out of it, the rest of my day is beautiful and happy, and I am happy for the next week or even two.

Though every once in a while I feel worse afterwards, after a beautiful experience, because I come back only to realize that this default world is the bad trip, haha. That always is a downer.

Anyone else out there do DMT for depression on occasion?


A main thing about this is that people always talk about set and setting, and that one should not do psychedelics when feeling depressed or frustrated or in a bad mood, whatever. I do think that the setting though matters a lot, like say doing DMT in a crowd of people making fun of you instead of alone in a forest Anyway, at least for DMT, it seems that doing it depressed or happy doesn't really matter and can have varying results. So when I hear about set and setting for DMT, I think "Hmmm, I prefer to do it while depressed because I feel absolutely wonderful afterwards." Maybe it is a contrast effect or just helps boost brain chemicals...

Affirmative it has been part of a long term mental state maintenance self improvement project .
For me without judgement or expectation that it will do anything.

The approach is an unspoken pact for lack of a better phrase. It's a way of connecting with nature and plants on a deep spiritual level . The fact that it improves my outlook on everything is the extra benefit .
I love what does to nature visually better than any art I've ever seen .

I find psilocybin mushrooms even better and more deeply healing when it comes to depression.

I had a "DMT-regiment" where I would smoalk low-medium doses weekly in addition to a breakthrough dose bi-weekly. It worked wonders for me, I felt great and consistently had a positive and constructive outlook on life. It kept me motivated and clear headed, and I could recognize negative patterns creeping into my life as they occurred; whether it was substance use, being lazy with my work, not paying attention to my body, etc...

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Nathanial what kind of doses were you at when you mention "visionary" 3.5? 5? 5+?

Caapi brew and/or 'pure alkaloid caapi extracts' (google them, they are out there) work wonders for depression, leaving strong afterglow for days, nature's miracle. As over 80% of the brain's 5-HT receptors are 5-HT1a receptors, the agonism of THH and other related compounds in caapi are very effective imho. Nausea can be avoided by using pure alkaloid extracts. Peak effects from caapi are felt some 5 hours later, which then last strongly for another 10 hours after that, as the half-life of tetrahydroharmine is 11 hours. Still possible to easily go to sleep but wake up feeling like a million dollars the next day and into the whole next day. You may loose a few hours sleep due to the stimulating nature of THH, but it's better than being depressed all week long imho. Fish oil helps too.

I went thru the death of a beloved one 3 weeks ago, and after 2 weeks of severe depression, found it to be the best thing for helping me to want to pick up the pieces again somehow and move on, mood much improved after dreaming on it. Death and Loss to me is the most devastating thing a person can go thru, it feels like a huge chunck of your heart is ripped out after the loss of a loved one.

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Blessings
~ND