I think that answer is no, at least for most people, but I'm curious if there is anyone else that this happens too.
I'm interested neurologically mostly.

With complete reliability a few hours after doing harmalas, whether I take more harmalas or not, when I smoke DMT I get 1/3 or less the effects and this last several hours I don't know the exact length but it is less than 24 hours until I can get the effects again.

When I smoke or sublingually take the harmalas then I get potentiation and all the good harmalas do when mixed with DMT but I am limited to once a day which is odd. I have accepted that the benefits of the harmalas outweigh the once-a-day issue but still I'm curious.

Anyone else get this, or anything close? When I take harmalas orally then I get potentiation up to 7 or 8 hours later, unsure about tolerance after that though.

I've noticed this too, that the first two or three blast offs are noticeably stronger than the following ones... I wonder why is this with the harmalas.

This is pretty much the same thing that happens to me. When I do sublingual caapi + dmt sessions, after about one hour, during the 3rd-5th blast off(I like to blast off several times sometimes) the visuals are almost non existent, even at high doses.
Without sublingual harmalas I don't have this loss of visual aspect in the blastoffs.
Anyone else with these kind of effects?

yup, while having not dosed only harmala and done dmt sessions. i have dosed harmala, lsd, and then dmt a few hours later at or around the peak. it's grrrreat then but yeah, it's all down hill from there until, say, the next day. a few hours after harmala i get nothing from dmt. what is with this?