I think a good deal of amnesia stems from some left-brain/right-brain incompatibility. For the record, this is just a half-baked theory

but the DMT experience seems to be a predominantly right-brain kind of experience in the sense that it is visual, symbolic, wholistic...As most of us experience reality dominantly through the left-brain (ego) relying heavily on language to break down reality into its individual components with analysis and labels, I believe that the information that is processed in hyperspace is largely incompatible with linguistic analysis and therefore becomes difficult to consolidate into everyday memory. Going off what Tek was saying in regards to McKenna's strategy (which I use often, even though I never heard McKenna talk about it), is that if you cannot get the ego to engage the sensory information sufficiently while the experience is taking place, then much of it will be lost. Additionally, much of everyday memory is based much more heavily on expectations of how things probably went as opposed to actually remembering it for what it was. People who haven't journeyed much (or who get a much heavier journey than usual) have particularly weak expectations and poor labels which make for particularly weak memories.
"Science without religion is lame. Religion without science is blind" - Albert Einstein
"The Mighty One appears, the horizon shines. Atum appears on the smell of his censing, the Sunshine- god has risen in the sky, the Mansion of the pyramidion is in joy and all its inmates are assembled, a voice calls out within the shrine, shouting reverberates around the Netherworld." - Egyptian Book of the Dead
"Man fears time, but time fears the Pyramids" - 9th century Arab proverb