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NDRI and MAOI Options
 
Trev_sunyata
#1 Posted : 2/1/2019 3:18:38 AM
It's ok to take MAOIs with NDRIs right?
This one's related to phenylethylamines.
Are there any drugs that interact badly with NDRIs?

Side question I thought of while typing:
Would an MAOI be a good idea to take before ingesting LSA extract?
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ShamensStamen
#2 Posted : 2/1/2019 4:00:58 AM
It's the Serotonin and Noradrenaline you gotta be concerned about, Dopamine not so much as MAO-A inhibition doesn't seem all that Dopaminergic ime. I've taken some Isopropylphenidate with Moclobemide a couple times and didn't notice really any issues, also have taken Mucuna/L-Dopa with Moclobemide, as well as Harmalas/Rue, seems to work fine, but too much Noradrenaline could cause a hypertensive crisis or increased heart rate and such, not inherently dangerous, but could be problematic with a high enough dosage imo, i'd say give Mucuna a try, works nicely, been taking it twice a day everyday for a year and a month now.
 
dreamer042
Moderator | Skills: Mostly harmless
#3 Posted : 2/1/2019 5:51:25 AM
Harmalas have fairly significant nor-epinephrine activity, such a combination is contraindicated. As a general rule of thumb it's typically not a good idea to mix any reuptake inhibitor with a RIMA/MAOI.
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Visual diagram for the administration of dimethyltryptamine

Visual diagram for the administration of ayahuasca
 
 
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