When I started on pharma I decided to sequentially try all levels of processing systems. I didnt have fine ACRB powder, but rather course powder and bark chunks, so I did not try just swallowing the ACRB but my first trials were crude syrian rue brew and crude ACRB brew. That most certainly works. You might waste a lot of ACRB if you dont get the dose and timing of harmalas optimized for your own body, and its more purgative, but it works.
If I were to take capped ACRB powder I would not dose it an
hour after the harmalas. I might dose some harmalas an hour before washing down the pills with more harmalas, but only if I could limit the amount of harmaline consumed. I dont like substantial amounts of harmaline but I can take pure harmine by the gram
So, yes, crude can work.
Keep notes and experiment intelligently.