IMHO, "being ready" is a multiple faced animal:
1) Where you "ready?" for that first
- school day
- ride a bike
- swimming lesson
- sex with partner
- job
- death of a relative
- etc etc...
in absolute terms: no, because one can't be ready for anything new, which is the ultimate definition for something new.
2) But "being ready" defined like "Will I be able to pull of that job"?
Then the answer is likely: yes.
(If not mentally/psychologically compromised, if the context is sane)Even when accidentally hyper-slapped, people come back and live on, be it with a somewhat changed perspective (i.e. humbled and full of respect).
The degree of how good the aligning will succeed with the new experiment, largely depend on adaptation factors, of which dose is a mandatory, along with set-setting. Very cliche
3) "Being ready" as in "Is it the right time" to discover the molecule?
Intuition, feeling called, a feeling as this really belongs on the path, .... , are my indicators of choice. I won't claim that any other way is wrong.