Just got some Rue, what is the best way to run this the first time. And can anyone explain how it effects a trip if the dmt is smoked?
As far as Ive read 2g Rue with 100mg DMT 30 mins later?
How long can the effects last for?

Syrian rue potentiates , lengthens and changes the character when combined of psychdelic experiences a quick search will provide more information. Search for pharmahuasca, ayahuasca vaporhuasca.

Yes, I am making it into Harmalas, the question is do I need to freebase it, or can it be kept as a salt for smoking?

Freebase is much better.

Keep in mind the filtering is going to be a real pain. Rue brews are a sludgy mess but the pure harmalas are worth the time & effort if your patient or if you have a vaccum filtration setup.

I suggest trying a few rue brews on their own orally as well.
Even without the dmt, low dose rue (2-3g) is actually nice once you get past the taste.
Very calm, meditative mindset & it.s easy to drift off into a comfortable sleep.
It's very strange but i always end up with very mild visions fading into lucid dreams.
Harmalas in that dosage with no dmt do not seem to induce vomiting the way they do when you combine the two.

Please do some research, there is a lot of information in this forum already that will answer most of your questions and also some of the questions you hadn't thought of yet.

In general, I'd advise you to start with rue without any additives. Extracts from rue are easier to dose and have less body load.


Do not smoke 100 mg of DMT after ingesting 2g of rue (or equivalent)! You will have a very rough ride! Since rue makes the DMT work cumulatively, you can start with very low doses and smoke several small additional doses of DMT, which will steadily increase the effects.


At least 30 minutes if smoked.

If both the harmalas and the DMT is taken orally, at least 3 to 4 hours. For the oral route I advise to take an extract of rue and DMT together (no wait) and a dose of 150 mg harmala and 50 mg DMT. You can follow up with 50 mg harmala and 25 mg DMT combined after an hour. If you use plain rue, the uptake of the harmalas becomes unpredictable and you may need more of it and ingest more DMT. Use an extract if you can or at least brew a tea.

Be careful with the potentiating effects of rue. Read up on MAOI interactions, particularly those with SSRI's like prozac and MDMA, those are the dangerous ones, tyramine is a nuisance at most. Start with harmalas only, so you can get to know them before you start combining them with DMT.

Do your research and be careful.

@ concombres
I have filtered multiple times, finishing with a tightly packed cotton pad inside funnel tube. It resembled coffee once finished.

@ pitubo
I definitely meant 100mg dmt orally. as seems to be a conservative starting dose. And im 100kg/220lb also.
I have also seen the list of MAOI interactions and dangers, which originally put me off the idea of a MAOI, but my curiosity got the better of me.


So I have decided to go the Changa route for the benefits which are: slower onset meaning no rushed smoking and increased trip duration.

I am currently crystallizing freebase harmala as I type. This is my first time making changa ,as far as I know I will make it 1:1:1 harmala freebase, nn dmt, peppermint leaf.

I don't generally smoke anything so I guess I will have to go buy a bong or pipe/cone to smoke from.