Recently took the plunge with 1g of very pure synthetic mescaline hcl. I had split 2g with three people on two occasions previously so ingesting 666mg, give or take, per person. I had learned from previous times how important music is with high dose mescaline experiences. I know some people have had ‘meh’ experiences with music when it comes to mescaline, but at high doses music is really transformed, beyond anything else I’ve experienced bar LSD.

I wanted to push the boat out a bit this time and ingest 1g. A friend was lodging with me and has been for a few months and we would be parting ways very soon, this would be our last trip together. He also seemed keen to push the boat out and ingest 1g as well, we discussed the potential power of this dose, but he has some prior experience of psychedelics and viewed this as a one off, once in a life time type experience. We put the mescaline in some empty ‘00’ capsules and washed them down with grapefruit juice before midday, having fasted since waking. We were in good spirits and good health and had the house to ourselves for the weekend. We took it around noon on Saturday so had the rest of the weekend to do as we pleased. Some people reported much extended trips with higher doses...my experience didn't last any longer than my previous times. My friend tried a tiny bit before dosing to test for any potential allergic reaction, none was noted.

We had prepared the living room so it was cosy, got it nicely planted out, incense lit, music made accessible, purge bucket on standby. After dosing we lay down and awaited effects and likely an inevitable purge. My friend started feeling very nauseous after half an hour, I was ok till about the hour mark when I quite suddenly needed to purge. It was pretty stress free as purges go, grapefruit juice flavoured, and I felt much better afterwards. I noticed the bathroom floor was beginning to crawl with patterns. It was interesting looking out of the living room window, as we had done before on truffles. The mescaline was less overtly visual than the truffles. Colours were certainly vivid and there was patterning, but it was softer than on the truffles.

With mescaline it seems one gets the hangover out of the way early on, i.e. the nausea, and you feel good after this, in a fashion reversed compared to stimulants or alcohol (if you’re vomiting on the latter, by then it’s far too late). After the nausea of the come up, I drifted into a VERY dream like state. We just wanted to lie down and be cosy, and we drifted into deeper states of dream like relaxation.

Music was incredible. So liquid and voluptuous, and you could really drift away on it. From where I was lying I could see the clouds and the music and the canvas of clouds was a great combination. The feeling was one of powerful bliss and contentment…not a shallow or superficial feeling, I’m talking deep. A dreamy, blissful, euphoric trance. VERY sensual, but not overtly sexual, almost post orgasmic. It reminded me a lot of MDMA in some respects. A very body orientated feeling also which was nice, much more so than LSD say which is more in your head. We were content to lay and be saturated by this feeling, it was a very benign and soothing feeling, and I could feel myself vibrating slightly.

I found the experience to be, even at this dosage, very warm and benign. It would have been very hard I think to freak out on, it was such a warm soothing blanket of a feeling, with no sharp edges. My friend felt the same, despite initial negative feelings due to the nausea. It took a while to peak, stayed there a while, and then very gradually went back down to Earth after a good few hours. After four hours or so it had definitely peaked.

At some point we had a smoothie as we hadn’t eaten and yet and were starting to get hungry, and we smoked a little herb which was a nice addition. Then we went for a walk to a local park, and it felt good to have an explore, and there was no real paranoia or difficultly integrating into the real world (and quite a busy town).

This was my most pleasurable mescaline experience to date. In a purely hedonistic sense anyway. To be honest I felt very little difference in strength of this dose of 1g compared to my previous two 666mg experiences...in fact in some respects the latter experiences seemed to be stronger. I was a little intrigued/worried about a few reports about people tripping for a day or more, but I didn’t find it to last longer than any other previous experiences.

Pure mescaline is clearly different to ingesting cacti, which is not surprising given all the other alkaloids present (peyote in particular). My experience with peyote so far produced a more “complex” experience, despite it being a much lower dose of mescaline. Pure mescaline seems lighter and slightly more shallow, and dare I say superficial by comparison…it didn’t feel as mystical feeling as some of my previous cactus experiences, in the past some of these were combined with Syrian rue which definitely modulated the experience, but on cactus I recall very crystalline images and forms. Not on this mescaline though, all three times I have ingested this synthetic hcl I don’t really see particular images of things if that makes sense, just vague patterns. In some respects I feel cactus may allow one to go deeper in terms of healing, but this experience was very enjoyable, and I certainly have no regrets. Felt fine the next day.

My friend’s experience...


After swallowing 3 caps with a total of 1g mescaline on an empty stomach around 11.45, I went to lay in bed. It was my first time taking mescaline and I was a bit nervous and quite excited, particularly because of the high dose. After a mere 30min I started to become very nauseated, it was almost unbearable. I tried to keep in the mescaline as long as possible but after 45 mins I had to run to the bathroom to purge. I felt a lot better afterwards and effects started to build. Another 20-30 mins later, I had to purge again. Due to the intense nausea and a feeling of being poisoned I kind of regretted taking so much, at this point, but this didn’t last long. I went to lay on the floor, music was playing and I started feeling deeply relaxed. It feels a bit post-orgasmic, and definitely MDMA like. Patterns started to show on the carpet and wall but the most interesting was the music, it took your thoughts on a journey. It felt like my thoughts were surfing over waves of music and I just had to go with the flow. At not a single moment did the trip become too intense, it was very gentle, soothing and warm. After 4-5 hours it peaked, we had a little snack, listened to some more music and then went outside to have a walk. It was like we were walking on clouds. The effects gradually decreased, we smoked some herb and watched a film. We felt pretty chill and cosy for the rest of the eve. I went to bed around 0.30 but had trouble falling asleep. After sleeping, felt fine with no hangover the next day. All in all was a great experience.

That's quite a lot of mescaline to take in one go!

Very well written, succinct report - it's interesting what you say about the lack of strong visual patterning. My experiences with cactus extracts (San Pedro) have had a similar euphoria with lack of paranoia or visual patterning, even as I pushed up the doses (although I have no numerical data to go by.)

It would have been interesting to analyse your emesis to see how much of the mescaline had been absorbed.

Some say split dosing is rather gentler on the stomach...

Thanks dude, and yeah it was, but absolutely no regrets, was definitely the most pleasurable of my three experiences with the synthetic mescaline hcl, and I would have absolutely no qualms about ingesting such a dose again. Interesting you have experienced similar things with the San Pedro extracts, even when pushing up the doses. It was at the suggestion of my source for this that it be taken in one go for the best effect, although I can see this may be somewhat rougher on the stomach. However the nausea was no worse for me on this dose than it was on the two previous lower dose sessions, and I think staggering the doses may prolong the period of nausea somewhat, nice to get that bit out of the way. If one is not used to mescaline though like my friend, staggering doses may be advantageous. I'm curious as to how much I absorbed...I did have it in my stomach for an hour, and when I purged it wasn't noticeably more bitter than grapefruit juice is alone, so I'm thinking I absorbed most of it.

Such a sweet and thorough "teacher-plant".
Only Per.Torch and Loph so far, hence glad to hear about up-dosed pure M., so thanks for sharing. The report did not really indicate the amphetamine-like effects that is often correlated with Mesc., actually a bit opposite, no?

No worries dude, was definitely a lighter and shallower experience than I have experienced with cactus in some respects, but it was very delicious no doubt about it, definitely my most pleasurable experience so far with mescalito in any form. I was expecting more of a stimulant effect when I first dabbled with pure mescaline but I found it to be the opposite of stimulating, it makes you want to lie down and get cosy (at least it did with me and everyone else that has partaken), and too much movement early on may result in nausea, quite different to LSD say. This time we did go for a walk 6-7 hours or so after dosing and once we were on the move it felt really nice to be walking, we felt floaty, like we were walking on clouds, and if the day had been nicer or we'd had access to more nature nearby we would have very likely gone for a much longer walk...the energy was there you just had to get moving in the first place.

I don't wonder if, at those really high doses, mescaline doesn't begin to have activity at various dopamine receptors as well as the normal set of 5-HTRs. That might explain why it has a more relaxed, opiate-like feel than lower doses.

I have to agree, Bancopuma, on the point of extract vs cactus.

I've only successfully pulled off cactus the once - it was my first mescaline trip and by far the most pleasurable trip I've ever had. I didn't manage to purge as I stupidly did it in smoothie form (or more molten gloop form) which didn't lend itself well to the whole throwing up business. That said, I was perfectly content with my dodgy gut, and was far too busy having an experience that would completely turn my life around.

Since that ++++ event, in which I sat in the woods and saw leaves turn from spring light green, to the dark green of summer, to the blend of colours of autumn, and back again, I have attempted to replicate it. First with a couple of failed attempts with cactus, and now with HCL.

The HCL has been beautiful in its own right, but nowhere near as groundbreaking. I actually ended up doing 800mg myself the other day, which was somewhat dampened thanks to some cross-tolerance with a potent Lucy trip a week before, but it was fantastic. Again, I didn't purge (although I did feel like it at one point), but I'm beginning to believe that my inability to do so is more due to my iron gut from years of holding my booze than anything else. The HCL is definitely easier to deal with in this regard!

I find mescaline to be, by far, the most beautiful of all the psychedelics. The purging/gut aspect definitely puts it in its own league - you quickly realise that mescaline is not here just for fun. However, the body high and sheer joy and connection with nature is something to behold, and I find my thinking to be a lot clearer and faster on mescaline than other psyches. I don't get confused. Instead, I find it easier to process my thoughts and to come to the conclusions I'm looking for.