I worked with white sage in a Navajo blessing ceremony last summer. The smoking mixture we were using was heavy with white sage, which combined with the other herbs of the mountain smoke, imparted a nice clean flavor and a clear headed psycho-activity.
The pipe was filled with the mixture and lit with a dried out corn cob which had been heated red hot in the coals of the fire. The medicine man proceeded to get it to a rolling burn blowing the smoke on the objects to be blessed and saying prayers to be carried up on the smoke. The pipe was then in turn passed around between all the participants who said their own prayers and blessings always blowing the smoke over the objects.
When the bowl was finished the medicine man emptied it out into his hand and dropped the ashes into a cup of water eating any leftovers from his palm. The water was then blessed and drank by the medicine man and passed around the circle with each participant taking a drink of the ashy water. Shortly thereafter another bowl would be loaded in the pipe and the process would begin all over again.
I don't know much moar about it other than thujone is supposed to the main active and it has many traditional uses as food, cleanser, and medicine.