Hey Dr_Nick,
keep in mind that the fact a plant shows MAO inhibition properties does not mean it will be suitable as an ayahuasca analogue.
First, you'd have to see how effective are those compounds. A quick search online returns
this document reporting phenols with inhibitory activity in mugwort, but the potency of those inhibitors ranges between 1 and 45 micromols (IC50 value), while for instance harmine has an IC50 of 2,5
nanomols (see this great post by Infundibulum about
inhibitors and IC50 values). In practice this means you would potentially need a thousand times the amount of mugwort inhibiting compounds to get equivalent effects to harmine, and in any case the ability of a MAOI to
activate other alkaloids may depend on other properties of the substance, besides IC50 values.
Second, you would need to isolate the potential MAOIs from another compounds in the plant that may be toxic or otherwise affect negatively the experience. More so if you would need a lot of plant extract to achieve the desired inhibition, perhaps too much to make it feasible, never mind safe.
Particularly for first experiences I would stay with botanicals that are well researched and are known to work safely when used properly. Syrian rue is not difficult to find.
Welcome to the Nexus.
"The Menu is Not The Meal." - Alan Watts