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Quinine as an alternative MAOI Options
 
k6
#1 Posted : 1/2/2023 5:44:13 AM
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Hi all, long time lurker and first time poster here. Also, apologies if this is in the wrong subforum or has been covered before.

I recently read that quinine, an alkaloid found in the bark of the cinchona tree and also commonly added to tonic water, can act as a competitive inhibitor of MAO ( https://www.jstage.jst.g...8/37/2/37_2_363/_article ). I was wondering if anyone has been able to achieve pharma/anahuasca type effects using quinine/tonic water and DMT?

best,
k6
 

Good quality Syrian rue (Peganum harmala) for an incredible price!
 
Loveall
#2 Posted : 1/2/2023 11:23:43 AM

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Quinine can be bad for tinitus, I would not personally use it. Has other side effects too.

Link to some data below. Tinitus appears usually within a month of regular use. Very high rates for females and older people.

https://www.ehealthme.com/ds/quinine/tinnitus/
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k6
#3 Posted : 1/9/2023 1:40:53 AM
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Thanks for the information and link loveall, definitely won't be consuming tonic regularly after reading this. I guess I'm still interested for curiosity's sake.. I might be willing to do an experiment..once or twice, but I'm a bit concerned about any contraindications, and I don't know if its really worth it with the accessibility of rue. Also knowing the correct dose could be a bit tricky to figure out..
 
Toshido
#4 Posted : 1/9/2023 7:43:35 AM

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k6 wrote:
Thanks for the information and link loveall, definitely won't be consuming tonic regularly after reading this. I guess I'm still interested for curiosity's sake.. I might be willing to do an experiment..once or twice, but I'm a bit concerned about any contraindications, and I don't know if its really worth it with the accessibility of rue. Also knowing the correct dose could be a bit tricky to figure out..


If you don't know or are having doubts it's always a good sign to just NOT do it. There are plenty of ways to get MAOI containing substances. Definitely don't want to be cutting corners with something that demands a lot of respect. With hallucinogens, it's most often best to play it safe than to learn from mistakes. IMO.
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k6
#5 Posted : 1/11/2023 6:28:19 PM
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Fair enough. Thanks for all the support and great information here at the nexus.

Best,
k6
 
 
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