downwardsfromzero wrote:I think it depends on how much ayahuasca you're using, and how much chocolate you're eating.
Anecdotally, a friend of mine got messed up intestines and glitchy liver function from using too much 'ceremonial' cacao for too long but that was with 75grams or more several times a week for a few months. He gave me his bag of caapi after that, so make of that what you will. I have no idea how much caapi, or even if, he was using at the time.
Normal amounts are less likely to cause such complications but if you're worried about it can't you just not eat chocolate?
My guess is that with such excessive amounts of cacao, liverdamage either comes from the theobromine and caffeine, or from the polyphenols, or combination of these compounds.
Caapi has, as far as i know, no effect on the theobromine and caffeine.
I don't know what enzymes are involved in the metabolism of these polyphenols. I've heard they have slight MAO inhibiting properties themselves though.
Anyway, i've always heard that chocolate is toxic for dogs and causes their liver to shut down because they don't metabolise theobromine very well, so i suppose that when the amounts of theobromine (and caffeine) taken exceed the human body's capacity for metabolising it properly, you could get simmilar problems.
In wich case the caapi was no major factor in your friends liverproblems. It doesn't realy sound like he had serotonergic syndrome because then he would probably have mentioned some other, more prominent symptoms as well.